Comments for Hydrobates http://alanrendall.wordpress.com A mathematician thinks aloud Wed, 11 Nov 2009 12:49:25 +0000 http://wordpress.com/ hourly 1 Comment on Watching T cells cross the blood-brain barrier by hydrobates http://alanrendall.wordpress.com/2009/11/09/watching-t-cells-cross-the-blood-brain-barrier/#comment-262 hydrobates Wed, 11 Nov 2009 12:49:25 +0000 http://alanrendall.wordpress.com/?p=742#comment-262 I just saw that in the same issue of Nature as the article cited above (November 5 issue) there is a News and Views piece by R. Ranshoff discussing both that article and one by another group studying other aspects of the way that T cells cross the BBB. I did not look at this other article but I noticed that in that work Th17 cells seem to play a big role. I just saw that in the same issue of Nature as the article cited above (November 5 issue) there is a News and Views piece by R. Ranshoff discussing both that article and one by another group studying other aspects of the way that T cells cross the BBB. I did not look at this other article but I noticed that in that work Th17 cells seem to play a big role.

]]> Comment on Influenza vaccines by hydrobates http://alanrendall.wordpress.com/2009/11/05/influenza-vaccines/#comment-261 hydrobates Tue, 10 Nov 2009 21:40:15 +0000 http://alanrendall.wordpress.com/?p=729#comment-261 Hello Uwe I am not sure you should believe everything you read in 'Der Spiegel' on this subject. You might like to look at the comments on an article there on the home page of the Paul Ehrlich Institute (http://www.pei.de/) By the way, there must be some misunderstanding with the 'no vaccine for a virus' statement. For instance, I got vaccinated against yellow fever before I visited Cameroon. Hello Uwe

I am not sure you should believe everything you read in ‘Der Spiegel’ on this
subject. You might like to look at the comments on an article there on the home page of the Paul Ehrlich Institute (http://www.pei.de/)

By the way, there must be some misunderstanding with the ‘no vaccine for a virus’ statement. For instance, I got vaccinated against yellow fever before I visited Cameroon.

]]> Comment on Influenza vaccines by Uwe Brauer http://alanrendall.wordpress.com/2009/11/05/influenza-vaccines/#comment-260 Uwe Brauer Tue, 10 Nov 2009 16:13:38 +0000 http://alanrendall.wordpress.com/?p=729#comment-260 Hello I don't hope to start a "flamewar" on this, but the article http://www.spiegel.de/wissenschaft/mensch/0,1518,druck-637567,00.html unfortunately in german, gives some interesting insights. Tom Jefferson an expert in epidemics from the Cochrane Collaboration claims, that based on statistical analysis only 7% of all the infection which have flu like symptoms are actually caused by the by the influenca virus. Moreover washing the hands is the best protection. It calls his attention (and I must say mine) that the influenca virus is unique among all the other groups of virus in the sense that it is the only one for which a vaccine has been developed. Uwe Brauer Hello

I don’t hope to start a “flamewar” on this, but the article
http://www.spiegel.de/wissenschaft/mensch/0,1518,druck-637567,00.html
unfortunately in german, gives some interesting insights.

Tom Jefferson an expert in epidemics from the Cochrane Collaboration claims, that based on statistical analysis only 7% of all the infection which have flu like symptoms are actually caused by the by the influenca virus.

Moreover washing the hands is the best protection.

It calls his attention (and I must say mine) that the influenca virus is unique among all the other groups of virus in the sense that it is the only one for which a vaccine has been developed.

Uwe Brauer

]]> Comment on The blood-brain barrier by Watching T cells cross the blood-brain barrier « Hydrobates http://alanrendall.wordpress.com/2008/08/27/the-blood-brain-barrier/#comment-259 Watching T cells cross the blood-brain barrier « Hydrobates Mon, 09 Nov 2009 19:12:26 +0000 http://alanrendall.wordpress.com/?p=91#comment-259 [...] where detailed information is given on certain aspects of the way that activated T cells cross the blood-brain barrier during the development of the disease EAE in rats. In fact the authors were able to film the [...] [...] where detailed information is given on certain aspects of the way that activated T cells cross the blood-brain barrier during the development of the disease EAE in rats. In fact the authors were able to film the [...]

]]> Comment on H1N1 and the influenza pandemic of 1918 by Influenza vaccines « Hydrobates http://alanrendall.wordpress.com/2009/05/15/h1n1-and-the-influenza-pandemic-of-1918/#comment-257 Influenza vaccines « Hydrobates Thu, 05 Nov 2009 21:03:32 +0000 http://alanrendall.wordpress.com/?p=545#comment-257 [...] examples are H5N1 (which includes the recent ‘bird flu’) and H1N1 (which includes the pandemic of 1918 and the current ’swine flu’.) Influenza B does not carry a pandemic threat and will not [...] [...] examples are H5N1 (which includes the recent ‘bird flu’) and H1N1 (which includes the pandemic of 1918 and the current ’swine flu’.) Influenza B does not carry a pandemic threat and will not [...]

]]> Comment on The cosmic no hair theorem by Uwe Brauer http://alanrendall.wordpress.com/2009/10/15/the-cosmic-no-hair-theorem/#comment-255 Uwe Brauer Fri, 30 Oct 2009 10:53:26 +0000 http://alanrendall.wordpress.com/?p=703#comment-255 Hello Alan, let me ask a more precise question then. Does the energy in the case of the Einstein equations with a perfect fluid have some geometric or kinetic interpretation? I am especially interested in the interpretation for the part of the energy which corresponds to the fluid. Hello Alan,

let me ask a more precise question then. Does the energy in the case of the Einstein equations with a perfect fluid have some geometric or kinetic interpretation? I am especially interested in the interpretation for the part of the energy which corresponds to the fluid.

]]> Comment on The cosmic no hair theorem by Uwe Brauer http://alanrendall.wordpress.com/2009/10/15/the-cosmic-no-hair-theorem/#comment-254 Uwe Brauer Fri, 30 Oct 2009 10:49:51 +0000 http://alanrendall.wordpress.com/?p=703#comment-254 Right, since you did not answer I presumed the answer would be no. I do remember having made some calculations, but, since this is a long time ago, I am not sure whether it was trivial or difficult. I presume it was quite straightforward, but since it was basically a copy of Friedrichs original work I did not bother to write it up. Right, since you did not answer I presumed the answer would be no.
I do remember having made some calculations, but, since this is a long time ago, I am not sure whether it was trivial or difficult.

I presume it was quite straightforward, but since it was basically a copy of Friedrichs original work I did not bother to write it up.

]]> Comment on The cosmic no hair theorem by hydrobates http://alanrendall.wordpress.com/2009/10/15/the-cosmic-no-hair-theorem/#comment-253 hydrobates Fri, 30 Oct 2009 10:45:37 +0000 http://alanrendall.wordpress.com/?p=703#comment-253 I just realized that I only answered one of the two questions which Uwe asked. Concerning the second, it is plausible that Friedrich's techniques would work in the case of a radiation fluid but nobody has ever worked it out. I just realized that I only answered one of the two questions which Uwe asked. Concerning the second, it is plausible that Friedrich’s techniques would work in the case of a radiation fluid but nobody has ever worked it out.

]]> Comment on The cosmic no hair theorem by hydrobates http://alanrendall.wordpress.com/2009/10/15/the-cosmic-no-hair-theorem/#comment-251 hydrobates Mon, 26 Oct 2009 14:12:24 +0000 http://alanrendall.wordpress.com/?p=703#comment-251 Hello Uwe When talking about 'clever energy estimates' I was thinking of those used by Ringstrom. As I understood from Speck's talk the case with a fluid is a lot more difficult but I know very little about the details. As to the orginal estimates I would sum up the situation as follows. The only tool available is energy estimates and so what is necessary (and difficult) is to find the right energy functionals. One procedure which is useful in doing this is to identify what are likely to be the main terms and produce a simplified model system by discarding all other terms Analysing the dynamics of the model system then helps to guess how to treat the original system. Doing these things has a lot to do with intuition and is anything but a deterministic algorithm. Hello Uwe

When talking about ‘clever energy estimates’ I was thinking of those used by Ringstrom. As I understood from Speck’s talk the case with a fluid is a lot more difficult but I know very little about the details. As to the orginal estimates I would sum up the situation as follows. The only tool available is energy estimates and so what is necessary (and difficult) is to find the right energy functionals. One procedure which is useful in doing this is to identify what are likely to be the main terms and produce a simplified model system by discarding all other terms Analysing the dynamics of the model system then helps to guess how to treat the original system. Doing these things has a lot to do with intuition and is anything but a deterministic algorithm.

]]> Comment on The cosmic no hair theorem by Uwe Brauer http://alanrendall.wordpress.com/2009/10/15/the-cosmic-no-hair-theorem/#comment-250 Uwe Brauer Mon, 26 Oct 2009 11:31:59 +0000 http://alanrendall.wordpress.com/?p=703#comment-250 Hello could you say a word or two about these clever energy estimates discovered by Speck et al? By the way, I am not entirely sure about this, but wouldn't Friedrichs techniques work for a perfect fluid with p=1/3\rho, that is the trace of the energy tensor vanishes. Hello

could you say a word or two about these clever energy estimates discovered by Speck et al?
By the way, I am not entirely sure about this, but wouldn’t Friedrichs techniques work for a perfect fluid with p=1/3\rho, that is the trace of
the energy tensor vanishes.

]]>